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Best Joint Supplement

Ultra Cissus™

Ultra Cissus™



Ultimate Joint & Bone Health


  • May Protect Against Bone Loss*
  • May Facilitate Weight Loss*
  • Reduces Joint Discomfort*
  • Improves Relaxation*
  • Antioxidant Effects*
  • 60 Servings






Cissus Quadrangularis is an ayurvedic herb that has traditionally been used to combat joint pain and weak bones, which earned it the nickname “Bone Setter.” The joint and bone claims have since been substantiated by modern research, and even more has been discovered about Cissus Quadrangularis.


  • In a study conducted on athletes, daily supplementation with Cissus Quadrangularis improved aggregate pain ratings during daily activities as well as upper and lower body exercise.
  • One study has noted a decrease in body weight following improved appetite control in an overweight subject population.
  • Cissus may increase serotonin levels, improving relaxation and decreasing stress.
  • Other health effects include reductions in total cholesterol and triglycerides, oxidative stress, and improved libido and sexual health.


The best part is that each of these studies were using a standardized, though inferior source of, Cissus Quadrangularis compared to Ultra Cissus™. The research has used Cissus with a 2.5% ketosterone standardization. Ultra Cissus™ uses a 40% ketosterone standardization, which means you get greater effects from one potent dose! Beneficial effects of Cissus Quadrangularis have been noted with doses of 300 - 3200mg per day – just one dose of Ultra Cissus™ provides the equivalent of 25,600mg of competitors! If you’re looking for the best source of Cissus Quadrangularis, you have found it in Ultra Cissus™.


*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Supplement Facts

 Best Joint Supplement

Ingredient Profile

Cissus Quadrangularis Extract

Ultra Cissus™ is standardized at 40% total ketosterones and 20% 3-ketosterone, the primary active ingredients in the herb. Compare this to just 2.5% in other products.


  • Participants supplementing with Cissus Quadrangularis have reported a 33% decrease in their perceived joint pain during exercise and activities of daily living after just 8 weeks (Bloomer, 2013).
  • Body weight loss ranging from 4.8 - 6.9% in 8 weeks has been reported with Cissus supplementation.
  • Rodent studies have demonstrated that supplementation with Cissus can prevent bone loss.
  • Early research supports further exploration for the ability of Cissus to optimize hormone levels in men and women, potentially enhancing body composition and sexual health.

Q: What is the best way to use Ultra Cissus™?

A: As a dietary supplement, consume 1 serving (2 capsules) of Ultra Cissus™ per day. For optimal absorption, take 1 capsule with breakfast and 1 capsule with dinner. Because Ultra Cissus™ may enhance relaxation, it is recommended not to consume prior to intense exercise.


Q: Can I take Ultra Cissus™ with other supplements?

A: Yes. There are currently no known contraindications with other products. We recommend stacking Ultra Cissus™ with Alpha Lipoic Acid and L-Carnitine for antioxidant support.



Cissus Quadrangularis

  1. Bloomer, R. J., Farney, T. M., McCarthy, C. G., & Lee, S. R. (2013). Cissus quadrangularis reduces joint pain in exercise-trained men: a pilot study. The Physician and sportsmedicine41(3), 29-35.
  2. Oben, J. E., Enyegue, D. M., Fomekong, G. I., Soukontoua, Y. B., & Agbor, G. A. (2007). The effect of Cissus quadrangularis (CQR-300) and a Cissus formulation (CORE) on obesity and obesity-induced oxidative stress. Lipids in Health and Disease6(1), 4.
  3. Oben, J., Kuate, D., Agbor, G., Momo, C., & Talla, X. (2006). The use of a Cissus quadrangularis formulation in the management of weight loss and metabolic syndrome. Lipids in Health and Disease5(1), 24.
  4. Oben, J. E., Ngondi, J. L., Momo, C. N., Agbor, G. A., & Sobgui, C. S. M. (2008). The use of a Cissus quadrangularis/Irvingia gabonensis combination in the management of weight loss: a double-blind placebo-controlled study. Lipids in health and disease7(1), 12.
  5. Chopra, S. S., Patel, M. R., & Awadhiya, R. P. (1976). Studies of Cissus quadrangularis in experimental fracture repair: a histopathological study. The Indian journal of medical research64(9), 1365-1368.
  6. Aswar, U. M., Mohan, V., & Bodhankar, S. L. (2012). Antiosteoporotic activity of phytoestrogen-rich fraction separated from ethanol extract of aerial parts of Cissus quadrangularis in ovariectomized rats. Indian journal of pharmacology44(3), 345.

California’s Proposition 65 entitles California consumers to special warnings.

WARNING: Cancer and Reproductive Harm -